Ellen Sidransky Selected Research

Parkinsonian Disorders (Parkinsonism)

1/2022	Comparison of Transcranial Sonography and [18 F]-Fluorodopa PET Imaging in GBA1 Mutation Carriers.
1/2021	The Role of Exosomes in Lysosomal Storage Disorders.
10/2020	Pro-cathepsin D, Prosaposin, and Progranulin: Lysosomal Networks in Parkinsonism.
1/2020	A characterization of Gaucher iPS-derived astrocytes: Potential implications for Parkinson's disease.
1/2020	Longitudinal Positron Emission Tomography of Dopamine Synthesis in Subjects with GBA1 Mutations.
1/2020	Substrate reduction therapy for GBA1-associated Parkinsonism: Are we betting on the wrong mouse?
1/2020	Glucocerebrosidase as a therapeutic target for Parkinson's disease.
1/2019	GBA1-associated parkinsonism: new insights and therapeutic opportunities.
1/2019	Glucocerebrosidase and its relevance to Parkinson disease.
2/2017	The Complicated Relationship between Gaucher Disease and Parkinsonism: Insights from a Rare Disease.

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Ellen Sidransky Research Topics

Disease

82	Gaucher Disease (Gaucher's Disease) 05/2022 - 01/2002
41	Parkinson Disease (Parkinson's Disease) 01/2022 - 01/2004
30	Parkinsonian Disorders (Parkinsonism) 01/2022 - 01/2004
12	Synucleinopathies 01/2019 - 01/2006
5	Neurologic Manifestations (Neurological Manifestations) 10/2020 - 01/2015
4	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2020 - 05/2014
4	Dementia (Dementias) 01/2020 - 03/2008
3	Disease Progression 01/2018 - 08/2002
3	Lysosomal Storage Diseases (Lysosomal Storage Disease) 03/2016 - 05/2010
3	Lewy Body Disease (Lewy Body Dementia) 06/2013 - 01/2006
3	Glycogen Storage Disease Type II (Pompe's Disease) 09/2012 - 07/2009
3	Fabry Disease (Fabry's Disease) 12/2010 - 08/2009
2	Anemia 01/2019 - 01/2002
2	Myoclonic Epilepsies (Myoclonic Encephalopathy) 11/2011 - 09/2004
1	Neuroinflammatory Diseases 01/2020
1	Gliosis 01/2020
1	Movement Disorders (Movement Disorder) 01/2020
1	Thrombocytopenia (Thrombopenia) 01/2019
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2019
1	Rabies (Hydrophobia) 03/2016
1	Tetanus 03/2016
1	Neoplasms (Cancer) 02/2016
1	Kufor-Rakeb syndrome 05/2013
1	Neuronal Ceroid-Lipofuscinoses (Neuronal Ceroid Lipofuscinosis) 05/2013
1	Male Infertility (Male Sterility) 06/2012
1	Globoid Cell Leukodystrophy (Krabbe Disease) 09/2011
1	Inborn Genetic Diseases (Disease, Hereditary) 08/2007
1	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 04/2005

Drug/Important Bio-Agent (IBA)

86	Glucosylceramidase (Glucocerebrosidase)IBA 05/2022 - 01/2002
54	EnzymesIBA 08/2021 - 01/2002
19	SynucleinsIBA 10/2021 - 07/2004
17	Glucosylceramides (Glucocerebrosides)IBA 01/2019 - 01/2002
14	Proteins (Proteins, Gene)FDA Link 01/2020 - 08/2002
8	sphingosyl beta-glucosideIBA 01/2022 - 08/2002
5	Dopamine (Intropin)FDA LinkGeneric 01/2022 - 08/2012
5	GlycolipidsIBA 01/2016 - 03/2003
4	AcidsIBA 05/2022 - 05/2010
4	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2018
4	Pharmaceutical PreparationsIBA 01/2019 - 07/2010
4	GlycosphingolipidsIBA 09/2011 - 08/2009
3	LipidsIBA 01/2019 - 08/2002
3	Amyloid (Amyloid Fibrils)IBA 01/2019 - 08/2011
3	CeramidesIBA 01/2016 - 05/2008
3	Lysergic Acid Diethylamide (LSD)IBA 09/2012 - 05/2010
2	HydrolasesIBA 10/2020 - 01/2015
2	alpha-SynucleinIBA 01/2020 - 09/2004
2	Levodopa (L Dopa)FDA LinkGeneric 04/2016 - 01/2006
2	Glucose (Dextrose)FDA LinkGeneric 01/2016 - 05/2008
2	Lysosomal Membrane ProteinsIBA 04/2013 - 11/2011
2	Complementary DNA (cDNA)IBA 11/2011 - 03/2002
2	GalactosidasesIBA 12/2010 - 07/2010
2	globotriaosylceramide (globotriosylceramide)IBA 12/2010 - 08/2009
2	alpha-Glucosidases (Acid Maltase)IBA 05/2010 - 07/2009
2	Fluorescent Dyes (Fluorescent Probes)IBA 08/2009 - 07/2009
2	DNA (Deoxyribonucleic Acid)IBA 04/2005 - 03/2003
1	Biological ProductsIBA 01/2022
1	ProgranulinsIBA 10/2020
1	procathepsin DIBA 10/2020
1	Retinaldehyde (Retinal)IBA 01/2020
1	Glial Fibrillary Acidic ProteinIBA 01/2020
1	fluorodopa F 18IBA 01/2020
1	Cysteine (L-Cysteine)FDA Link 01/2019
1	CathepsinsIBA 01/2019
1	Histone Deacetylase InhibitorsIBA 01/2019
1	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 01/2018
1	neutrophil cytosol factor 67KIBA 01/2017
1	Indicators and Reagents (Reagents)IBA 04/2016
1	Peptides (Polypeptides)IBA 03/2016
1	Glycoproteins (Glycoprotein)IBA 03/2016
1	Tetanus ToxinIBA 03/2016
1	InflammasomesIBA 02/2016
1	AmidesIBA 02/2016
1	InterleukinsIBA 02/2016
1	Interleukin-6 (Interleukin 6)IBA 02/2016
1	CytokinesIBA 02/2016
1	NCGC607IBA 01/2016
1	Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)IBA 01/2016
1	CatecholaminesIBA 09/2015
1	Dihydroxyphenylalanine (Dopa)IBA 09/2015
1	SolutionsIBA 01/2015
1	Membrane LipidsIBA 01/2015
1	Membrane Proteins (Integral Membrane Proteins)IBA 03/2014
1	Messenger RNA (mRNA)IBA 03/2014
1	A-factor (Streptomyces)IBA 02/2014
1	MicroRNAs (MicroRNA)IBA 01/2014
1	LipofuscinIBA 05/2013
1	P-type ATPasesIBA 05/2013
1	GlucosidasesIBA 09/2012
1	SaposinsIBA 07/2012
1	Molecular Chaperones (Chaperone, Molecular)IBA 06/2012
1	Enzyme ActivatorsIBA 01/2012
1	Psychosine (Galactosylsphingosine)IBA 09/2011
1	alpha-Galactosidase (Beano)IBA 08/2009
1	GlycogenIBA 07/2009
1	Leucine (L-Leucine)FDA Link 08/2006
1	Phosphotransferases (Kinase)IBA 08/2006

Therapy/Procedure

21	Therapeutics 08/2021 - 02/2007
8	Enzyme Replacement Therapy 01/2018 - 02/2007
1	Drug Therapy (Chemotherapy) 08/2021
1	Duration of Therapy 05/2016